Session 5: Drug Discovery and Screening
The Drug Discovery Process involves many different stages and series of actions. Typically, it can be divided into four main stages: Early Drug Discovery, Pre-Clinical Phase, Clinical Phases, and Regulatory Approval. Let's explore the major steps that are taken in each of these stages to develop a new drug.
Drug discovery is a process where a new drug or medication is discovered and aims to identify a compound therapeutically useful in curing and treating disease. It includes a wide range of scientific divisions, including biology, chemistry, and pharmacology. This process associates with the identification of candidates, synthesis, characterization, validation, optimization, screening, and assays for therapeutic efficacy.
Drug screening is a process where potential drugs are identified and optimized before the selection of a candidate drug to progress to clinical trials. It can involve screening large volumes of chemicals for a particular biological activity in high-throughput screening assays. Drug screening mainly includes In-vivo and In-vivo models drug screening.
·Discovery and Development.
·Preclinical Researches
·Clinical Researches
·FDA Review.
· FDA Post-Market Safety Monitoring.