Proteomics is the study of proteomes on a large scale. A proteome is a collection of proteins that are produced by an organism, system, or biological context. Target identification and validation, identification of efficacy and toxicity biomarkers from readily accessible biological fluids, and investigations into mechanisms of drug action or toxicity are all common applications of proteomics in the pharmaceutical industry.
Bioinformatics can help with gene expression and drug discovery by developing an objective and rational index of drug desirability for use in phenotypic screening studies that use gene expression profiles as phenotypes.
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